

| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 250mg | 360 pills | NZD1.20 | NZD481.18 NZD433.07 Best Price | |
| 250mg | 180 pills | NZD1.44 | NZD287.65 NZD258.89 | |
| 250mg | 90 pills | NZD2.17 | NZD217.04 NZD195.34 | |
| 250mg | 60 pills | NZD2.52 | NZD167.35 NZD150.62 | |
| 250mg | 30 pills | NZD3.37 | NZD112.43 NZD101.19 | |
| 500mg | 360 pills | NZD1.32 | NZD528.26 NZD475.43 Popular | |
| 500mg | 120 pills | NZD1.98 | NZD264.12 NZD237.70 | |
| 500mg | 90 pills | NZD2.40 | NZD240.58 NZD216.52 | |
| 500mg | 60 pills | NZD2.87 | NZD190.89 NZD171.80 | |
| 500mg | 30 pills | NZD3.53 | NZD117.66 NZD105.89 |
Disclaimer: This information is for general guidance only and does not replace professional medical advice. Always follow your healthcare professional’s instructions and the official patient leaflet that comes with your medicine.
Principen is a brand name for an antibiotic called ampicillin, which belongs to the penicillin family. It is used to treat certain bacterial infections by stopping the growth of bacteria.
Like other antibiotics, Principen does not work for viral illnesses such as colds, flu, or most cases of bronchitis. It should only be used when a healthcare professional has determined that a bacterial infection is present or likely.
In New Zealand, the use of Principen may depend on local rules and regulations regarding prescription medicines. Your pharmacist can confirm whether a prescription is required in your situation. Always use this medication exactly as prescribed by a doctor or pharmacist.
Principen is not a substitute for vaccines or good infection prevention practices. If you have had an allergic reaction to penicillins in the past, tell your healthcare professional before taking Principen.
Principen is used to treat a range of bacterial infections. It is generally chosen when the infecting bacteria are known or suspected to be susceptible to ampicillin, or when a clinician determines ampicillin is an appropriate part of treatment.
Common situations may include infections of the ears, throat, nose, and sinuses; certain chest infections; urinary tract infections; and some skin and soft tissue infections. The exact indications depend on local medical guidelines and what a clinician assesses for each patient.
Principen should not be used for viral infections or for people who do not have a proven or strongly suspected bacterial infection. It is part of a broader strategy to treat bacterial infections responsibly and to reduce the risk of antibiotic resistance.
Common indications are listed in the official patient information leaflet. If you are unsure whether Principen is suitable for your infection, speak with a doctor or pharmacist who can review your symptoms and medical history.
Principen contains ampicillin, which interferes with the way bacteria build their cell walls. This weakens the bacterial cell wall, causing the bacteria to die. The effect is described as bactericidal, meaning it can kill the bacteria causing the infection.
Because it targets a fundamental process in bacteria, Principen is only effective against bacteria that are susceptible to ampicillin. It does not work against viruses or other non-bacterial causes of illness.
Resistance to antibiotics can occur if the medicine is not used as directed. Finishing the full course, even if you feel better, helps reduce the chance that bacteria will become resistant. If you notice persistent symptoms or a worsening condition, contact a clinician for advice.
Principen is part of a broad approach to infection management that also includes good hygiene practices and, when appropriate, vaccination and preventive care. If you have questions about how this medicine works for your specific infection, discuss them with your doctor or pharmacist.
Take Principen exactly as prescribed. The form, dose, and duration will depend on the infection being treated and you as a patient. Your clinician will provide instructions tailored to you.
Principen is usually taken by mouth with a full glass of water. It can be taken with or without food unless your doctor advises otherwise. If you are using the oral suspension, shake the bottle well and use the provided measuring device to measure the correct amount. Do not use a household spoon to measure doses.
Consistency is important. Try to take doses at evenly spaced times each day. Do not skip doses or stop the medicine early unless advised by a healthcare professional. If you are unsure about the duration of treatment, ask your clinician for guidance.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the next dose to make up for the missed one. If you miss several doses, contact your doctor or pharmacist for advice on how to proceed.
Storage depends on the formulation. The oral suspension should be stored according to the product label, usually at room temperature away from direct heat and moisture. Keep all medicines out of reach of children. Do not use Principen after the expiry date stated on the packaging.
If you have trouble swallowing tablets or have a severe medical condition, talk to a healthcare professional about the best way to take Principen. If you become acutely ill with vomiting or severe diarrhea, seek medical advice promptly as this may affect dosing or require review of therapy.
Individuals with a known allergy to ampicillin, penicillins, or other beta-lactam antibiotics should not take Principen. An allergic reaction can be serious and may require immediate medical attention.
People who have previously had a severe reaction to one member of the penicillin family should be cautious and discuss alternatives with a clinician before taking Principen. This includes a history of hives, swelling, or difficulty breathing after penicillin exposure.
People with certain kidney problems may require dose adjustments or alternative treatments. A clinician will assess kidney function and overall health before confirming therapy with Principen.
In infectious mononucleosis, ampicillin can cause a distinctive rash in some individuals. If you have a history of mononucleosis or suspect it, tell your clinician before starting Principen.
Principen should be used with care in children, the elderly, and people with other chronic health conditions. Always discuss your full medical history with a clinician to determine if this antibiotic is appropriate for you or your child.
Allergic reactions to antibiotics can be serious. If you notice symptoms such as swelling of the face or lips, trouble breathing, or a severe skin reaction, seek urgent medical help. Do not continue taking the medicine without medical advice.
Antibiotics can disrupt the normal balance of bacteria in the gut. In some cases, this may lead to diarrhoea that is severe or persistent. If you develop tummy cramps, fever, or persistent diarrhoea during or after treatment, contact a clinician promptly.
Long or repeated use of antibiotics can contribute to antibiotic resistance and make future infections harder to treat. Use Principen only for infections that a clinician has identified as needing this antibiotic, and complete the full course unless advised otherwise.
Tell your doctor or pharmacist about all medicines you take, including OTC products, vitamins, and herbal supplements. Some medicines may interact with Principen or affect the treatment’s effectiveness. Your clinician can advise you on how to manage potential interactions.
Pregnant or breastfeeding individuals should discuss risks and benefits with a healthcare professional. In some circumstances, Principen may be used during pregnancy if clearly needed, but this decision should be made with a clinician.
Most people tolerate Principen well, but some experience side effects. Common effects include stomach upset, nausea, vomiting, or mild diarrhoea. A small number of people may develop a skin rash or itching.
Less common side effects can include vaginal itching due to fungal infection (thrush), or changes in taste. If you notice any persistent or unusual symptoms, contact your healthcare professional for advice.
Serious side effects require urgent medical attention. Seek help if you have signs of a severe allergic reaction, persistent fever, severe stomach cramps, or profuse diarrhoea with blood. Stop taking the medicine and seek guidance from a clinician if you experience any of these.
Always report serious or unusual side effects to your doctor or pharmacist so they can assess whether you should continue treatment or switch therapies.
Certain medicines can interact with Principen and may change how it works or increase the risk of side effects. It is important to tell your clinician about all medicines you are taking, including non-prescription drugs and supplements.
Some interactions may involve medicines that affect kidney function, gut bacteria, or bleeding risk. In other cases, one medicine may affect the level of another in the blood, which could require dosage adjustments or monitoring.
Because interactions can be specific to a person’s health status, a clinician will review your medications and tailor advice to you. If you start or stop any medicine during Principen therapy, inform your clinician promptly.
If you are unsure whether a medicine you are taking could interact with Principen, ask a pharmacist or clinician for guidance before continuing.
Pregnant and breastfeeding people should use Principen only if clearly needed and prescribed by a clinician. The potential benefits must be weighed against any possible risks to the developing fetus or infant.
Discuss your pregnancy status, plans to become pregnant, or breastfeeding with your clinician before starting Principen. Some medicines pass into breast milk and could affect a nursing baby; your clinician can advise whether this is appropriate for you.
Always inform your healthcare provider about all medicines you are taking during pregnancy or while planning pregnancy, so they can provide tailored guidance.
Below are common questions people have about Principen. If your question is not answered here, contact your pharmacist or doctor for personalised advice. Remember to consult the official leaflet for the most precise information about your product.
Antibiotics like Principen begin working to clear infection by inhibiting bacterial growth as soon as they start. Improvement in symptoms may vary depending on the type and severity of the infection, and not everyone will feel better at the same pace. If there is no improvement after a few days, or if symptoms worsen, contact your clinician for advice.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the next dose to make up for the missed one. If you miss multiple doses, contact your doctor or pharmacist for specific guidance.
Some medicines can interact with Principen. Tell your clinician about all medicines you are taking, including OTC products and supplements. Do not start or stop another medicine without consulting a healthcare professional if you are currently taking Principen.
No. It is important to complete the full course of therapy as prescribed, even if you feel better. Stopping early may allow bacteria to continue growing and could lead to a return of symptoms or antibiotic resistance.
Moderate alcohol use is not known to interfere directly with Principen for many people, but alcohol can raise the risk of certain side effects and may worsen stomach upset. If you are unsure, discuss alcohol use with your clinician during treatment.
Pregnant or breastfeeding individuals should use Principen only if clearly needed and prescribed by a clinician. Discuss your pregnancy or breastfeeding status with your doctor to understand potential risks and benefits for you and your baby.
Principen can be prescribed for children when appropriate. The dose and form will be chosen by a clinician based on the child’s weight, age, and the infection being treated. Always follow the clinician’s instructions for paediatric use.
Some antibiotics can cause diarrhoea. If you develop persistent or severe diarrhoea, or if you notice blood in your stool, seek medical advice promptly. Do not self-treat with anti-diarrhoeal medicines without guidance from a clinician.
Signs of a serious allergic reaction include swelling of the face, lips, tongue, or throat; severe itching or rash; trouble breathing or swallowing; or dizziness. If any of these occur, seek urgent medical help.
Contact your doctor if you experience any severe side effects, if symptoms worsen or do not improve after a few days, or if you develop new symptoms such as persistent fever, severe abdominal pain, or dehydration. Your clinician can reassess your treatment and make changes if needed.
Principen may require a prescription depending on local rules. In New Zealand, a clinician or pharmacist can advise whether a prescription is needed in your circumstance. Do not obtain or use antibiotics without appropriate medical supervision.
Do not stop early unless advised by a clinician. Stopping too soon can allow the infection to return and may contribute to antibiotic resistance. If you have concerns about side effects or tolerability, talk to your clinician before making changes.
Official patient information and the product leaflet provided with Principen supply. Information may be updated by regulatory authorities; always refer to the latest local guidance and your clinician’s advice.
New Zealand health guidance and pharmacist-informed resources can help you understand how to use antibiotics responsibly and safely. For any questions about your treatment, consult your doctor or pharmacist.
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