Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 100mcg | ||||
360 pill | 100mcg | NZD918.00 | NZD2.55 | |
270 pill | 100mcg | NZD701.02 | NZD2.60 | |
180 pill | 100mcg | NZD503.10 | NZD2.79 | |
120 pill | 100mcg | NZD371.96 | NZD3.10 | |
90 pill | 100mcg | NZD305.19 | NZD3.39 | |
60 pill | 100mcg | NZD238.42 | NZD3.98 | |
30 pill | 100mcg | NZD159.74 | NZD5.32 | |
Dosage: 200mcg | ||||
360 pill | 200mcg | NZD1,416.36 | NZD3.93 | |
270 pill | 200mcg | NZD1,094.46 | NZD4.05 | |
180 pill | 200mcg | NZD782.09 | NZD4.34 | |
120 pill | 200mcg | NZD660.48 | NZD5.51 | |
90 pill | 200mcg | NZD519.79 | NZD5.77 | |
60 pill | 200mcg | NZD362.42 | NZD6.03 | |
30 pill | 200mcg | NZD193.12 | NZD6.44 | |
20 pill | 200mcg | NZD133.51 | NZD6.68 | |
10 pill | 200mcg | NZD71.51 | NZD7.15 |
Misoprostol Description
Overview of Misoprostol
Misoprostol is a medication widely used for various medical purposes, primarily related to obstetrics and gynecology. It is a synthetic prostaglandin E1 analogue that works by causing the softening and dilation of the cervix and stimulating uterine contractions. Originally developed to prevent gastric ulcers, Misoprostol has found extensive application in pregnancy management, including medical termination of pregnancy and treatment of postpartum bleeding. Its effectiveness, affordability, and ease of use make it a popular option in modern medicine.
Uses and Benefits
One of the main uses of Misoprostol is in the medical termination of pregnancy. When combined with mifepristone, it significantly increases the likelihood of a complete and safe abortion within the first or second trimester. It is also used to induce labor in cases where the pregnancy needs to be prolonged or when the cervix requires ripening before surgical procedures. Additionally, Misoprostol is effective in controlling postpartum hemorrhage, a leading cause of maternal mortality worldwide. Its ability to induce uterine contractions rapidly aids in reducing bleeding after childbirth, making it a critical medication in emergency settings.
Mechanism of Action
Misoprostol works by binding to prostaglandin receptors in the smooth muscle layers, causing the muscles to contract. This activity leads to cervical ripening and induces contractions of the uterus. Its action on the cervix facilitates the expulsion of pregnancy products during medical termination, while its uterotonic effects are beneficial in controlling bleeding after delivery. The drug's ability to mimic natural prostaglandins makes it highly effective for these purposes and allows for controlled, predictable outcomes when used appropriately.
Dosage and Administration
The dosage of Misoprostol varies based on the intended use. For pregnancy termination, doses and administration routes are carefully determined by healthcare providers. It is commonly administered orally, vaginally, or sublingually, depending on the treatment protocol. In cases of postpartum bleeding, the drug is often given orally or vaginally. It is essential to follow medical guidance strictly to minimize side effects and maximize effectiveness. Self-administration without proper supervision is strongly discouraged, as incorrect dosing can lead to complications.
Potential Side Effects and Precautions
While Misoprostol is generally safe when used correctly, it can cause side effects. Common adverse reactions include nausea, vomiting, diarrhea, abdominal pain, and shivering. Some women may experience fever or chills after administration. Serious but rare complications include heavy bleeding, uterine rupture, or allergic reactions. It is vital to consult with a healthcare professional before using Misoprostol, especially for women with certain health conditions such as cardiovascular disease, liver or kidney problems, or previous uterine surgeries. Proper medical supervision ensures safe and effective use, reducing the risk of adverse outcomes.
Availability and Storage
Misoprostol is available through licensed pharmacies and healthcare providers worldwide. It is often supplied in tablet form, with various dosing strengths. To maintain its efficacy, the medication should be stored in a cool, dry place away from direct sunlight. Keep it out of reach of children and unapproved users. Since the drug can be used for sensitive medical procedures, obtaining it through a genuine source with proper prescription is crucial to ensure safety and legal compliance.
Conclusion
Overall, Misoprostol is a versatile and essential medication in reproductive health and emergency care. Its proven effectiveness in pregnancy termination, labor induction, and controlling postpartum hemorrhage makes it a vital tool for healthcare providers. When used appropriately and under medical supervision, Misoprostol offers a safe, affordable, and reliable option for women needing reproductive health interventions. Proper education about its use and potential risks is important for ensuring positive outcomes and maintaining safety in its administration.