Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 1% | ||||
5 tube | 1% | NZD86.62 | NZD17.33 | |
4 tube | 1% | NZD81.52 | NZD20.38 | |
3 tube | 1% | NZD71.33 | NZD23.78 | |
2 tube | 1% | NZD54.34 | NZD27.16 | |
Dosage: 5% | ||||
5 tube | 5% | NZD212.32 | NZD42.47 | |
4 tube | 5% | NZD183.44 | NZD45.86 | |
3 tube | 5% | NZD152.86 | NZD50.96 | |
2 tube | 5% | NZD118.89 | NZD59.44 |

Fluorouracil Description
Overview of Fluorouracil
Fluorouracil is a widely used medication in the treatment of various types of cancers. It belongs to a class of drugs known as antimetabolites, which interfere with the normal functioning of cancer cells. This medication is primarily administered to treat conditions such as colorectal, breast, stomach, pancreatic, and skin cancers. Its effectiveness is well-documented, making it a cornerstone in many chemotherapy protocols.
Mechanism of Action
Fluorouracil works by mimicking the natural building blocks of DNA andRNA. Specifically, it is converted inside the body into active metabolites that inhibit the enzyme thymidylate synthase. This enzyme is critical for DNA synthesis. By blocking its activity, fluorouracil prevents cancer cells from multiplying and growing. Since cancer cells often divide rapidly, they are more susceptible to these disruptions than normal cells, which is why the medication can selectively target tumor tissues.
Usage and Administration
This medication is typically administered either intravenously or topically, depending on the type of cancer being treated. For systemic cancers, healthcare professionals usually give it in a controlled clinical setting. The dosage and frequency depend on multiple factors, including the patient’s overall health, the specific cancer type, and the treatment plan. In some cases, it may be combined with other chemotherapy agents or targeted therapies to enhance effectiveness.
Possible Side Effects
Like all chemotherapeutic agents, fluorouracil can cause side effects. Common reactions include nausea, vomiting, diarrhea, and mouth sores. These are usually manageable with supportive care. More serious but less common side effects include low blood cell counts, which can increase the risk of infection or bleeding, and skin reactions such as redness or peeling, especially when used topically. Patients should be monitored regularly to manage and mitigate adverse effects effectively.
Precautions and Considerations
Before starting treatment with fluorouracil, patients should inform their healthcare provider about their medical history, especially any liver or kidney problems, which can affect drug metabolism. Pregnant or breastfeeding women are generally advised to avoid this medication due to potential risks to the baby. It is also important to discuss any other medications being taken, as fluorouracil can interact with certain drugs, altering its effectiveness or increasing toxicity.
Storage and Handling
Fluorouracil should be stored in a cool, dry place away from direct sunlight. Proper handling by trained medical personnel is essential to prevent contamination or accidental exposure, which could pose health risks. When used topically, the medication should be applied strictly following medical instructions to ensure safety and efficacy.
Effectiveness and Patient Experience
Patients often report that fluorouracil has been effective in shrinking tumors and controlling disease progression. However, its success heavily depends on correct dosing, cancer type, and individual response. Some patients experience significant side effects that can impact quality of life. Nevertheless, with proper management and supportive treatments, many individuals continue therapy and achieve positive outcomes.
Summary
Fluorouracil remains a vital medication in oncology. It offers a targeted approach to cancer treatment, disrupting the growth of malignant cells. Despite potential side effects, its benefits in combating various cancers make it a valuable option. Patients should always use fluorouracil under medical supervision to maximize safety and effectiveness, ensuring the best possible treatment results.