Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 2mg | ||||
90 pill | 2mg | NZD1,182.26 | NZD13.13 | |
60 pill | 2mg | NZD866.30 | NZD14.44 | |
30 pill | 2mg | NZD465.42 | NZD15.51 | |
Dosage: 5mg | ||||
90 pill | 5mg | NZD1,664.68 | NZD18.50 | |
60 pill | 5mg | NZD1,219.63 | NZD20.33 | |
30 pill | 5mg | NZD672.66 | NZD22.42 |
Chlorambucil Description
Overview of Chlorambucil
Chlorambucil is a chemotherapy medication used primarily in the treatment of certain types of cancer, including chronic lymphocytic leukemia (CLL), Hodgkin's lymphoma, and some other lymphatic or blood disorders. It belongs to a class of drugs known as alkylating agents, which work by interfering with the DNA replication process in cancer cells. This disruption prevents the cancer cells from dividing and multiplying, ultimately leading to their destruction.
How Chlorambucil Works
The drug functions by adding alkyl groups to the DNA molecule, which causes cross-linking between DNA strands. These cross-links hinder DNA replication and transcription, leading to cell death. While highly effective against rapidly dividing cancer cells, chlorambucil can also affect normal, healthy cells, which accounts for many of its potential side effects. Because of its mechanism, chlorambucil is often used in combination with other chemotherapy agents to enhance efficacy and reduce resistance.
Usage and Dosage
Chlorambucil is usually administered orally in the form of capsules. The dosage and schedule depend on the type of cancer being treated, the patient's overall health, and their response to therapy. It is important to follow the prescribing doctor's instructions closely. The medication is often taken on specific days of the week, with regular monitoring to assess effectiveness and manage side effects. Patients are advised to inform their healthcare provider about any other medications they are taking to avoid adverse interactions.
Potential Side Effects
Like many chemotherapy drugs, chlorambucil can cause a range of side effects. Common ones include nausea, vomiting, diarrhea, hair loss, and fatigue. Because of the impact on bone marrow cells, it can also lead to lowered blood cell counts, increasing the risk of infections, anemia, or easy bruising. Long-term use may cause complications such as secondary cancers or effects on fertility. It is essential for patients to undergo regular blood tests and follow-up evaluations to manage and mitigate these risks.
Precautions and Warnings
Patients scheduled to take chlorambucil should discuss their complete medical history with their healthcare provider. Those with existing bone marrow suppression, liver or kidney problems, or infections need special monitoring. Pregnant and breastfeeding women are advised to avoid this medication due to potential harm to the fetus or infant. As the drug suppresses immune function, patients should watch out for signs of infection and seek medical attention promptly.
Storage and Handling
Chlorambucil should be stored in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication beyond its expiration date. Proper handling is critical to ensure safety and maintain the drug's effectiveness. If any pills are broken or damaged, they should be disposed of properly according to medical guidance.