

| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 50mg | 360 pills | NZ$2.02 | NZ$969.41 NZ$727.06 Best Price | |
| 50mg | 180 pills | NZ$2.16 | NZ$519.54 NZ$389.65 | |
| 50mg | 120 pills | NZ$2.45 | NZ$392.81 NZ$294.61 | |
| 50mg | 90 pills | NZ$2.78 | NZ$332.62 NZ$249.46 | |
| 50mg | 60 pills | NZ$3.09 | NZ$247.08 NZ$185.31 | |
| 50mg | 30 pills | NZ$3.26 | NZ$129.86 NZ$97.40 | |
| 100mg | 360 pills | NZ$3.52 | NZ$1,688.57 NZ$1,266.42 Popular | |
| 100mg | 180 pills | NZ$3.56 | NZ$855.36 NZ$641.52 | |
| 100mg | 120 pills | NZ$3.64 | NZ$582.90 NZ$437.17 | |
| 100mg | 90 pills | NZ$3.75 | NZ$449.84 NZ$337.38 | |
| 100mg | 60 pills | NZ$3.85 | NZ$307.27 NZ$230.46 | |
| 100mg | 30 pills | NZ$4.35 | NZ$174.21 NZ$130.66 |
Disclaimer: This information is for educational purposes and is not a substitute for professional medical advice. Please consult your doctor or pharmacist about medications you take.
Pletal (cilostazol) is a phosphodiesterase-III inhibitor used to treat a specific symptom of peripheral artery disease known as intermittent claudication.
Active ingredient: cilostazol. Drug class: a PDE-III inhibitor with both vasodilating (blood vessel widening) and antiplatelet effects.
Primary purpose: to improve blood flow to the legs, reduce walking-related leg pain, and help you walk longer before symptoms appear, as part of a broader treatment plan.
In New Zealand, medicines are regulated for safety and access. Pletal may require a prescription depending on local rules. Always follow the instructions on the NZ patient information leaflet and from your clinician.
Pletal is prescribed for a symptom of peripheral artery disease called intermittent claudication. This condition is caused by narrowed arteries that reduce blood flow to the legs during activity.
The goal is to lessen leg pain and cramping that starts with walking and improves with rest. By improving blood flow, the medicine can help you walk farther and participate more in daily activities.
Pletal is most effective as part of a broader plan that includes physical activity, risk factor management (such as blood pressure and cholesterol control), and lifestyle changes. Your clinician will determine whether it is appropriate for you.
The medicine is not a general pain reliever for all types of leg pain. A clinician will assess whether Pletal is suitable for your specific situation.
Cilostazol works by inhibiting the enzyme phosphodiesterase-III in certain cells. This action raises the level of a molecule called cAMP inside cells.
Higher cAMP promotes relaxation of smooth muscle in blood vessels, leading to vasodilation (wider arteries). It also reduces the clumping together of platelets, which can help prevent clot formation in the small vessels.
The combination of better blood flow and reduced clotting tendency helps deliver more oxygen and nutrients to the leg muscles during activity. This can translate into less pain and greater walking ability for some people.
In practical terms, cilostazol addresses two aspects of the condition at once: improving the flow of blood to the legs and reducing the likelihood of small clots that can worsen symptoms during exertion.
Take Pletal exactly as prescribed by your clinician. Do not change the dose or stop taking it without medical advice.
Dosage is individualized. Your clinician may adjust the amount based on how you respond and what side effects you experience. Do not attempt to self-titrate without guidance.
Timing and food can affect absorption. It is generally advised to take the tablets with a meal or snack to support absorption, and to try to keep a regular dosing schedule each day.
Missed dose guidance: If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose. If it is nearly time for your next dose, skip the missed dose and resume your usual schedule. Do not take a double dose to make up for a forgotten one.
Administration notes: Swallow tablets whole with a glass of water. Do not chew or crush the tablets unless your clinician tells you otherwise. Store as directed on the label or information leaflet.
Do not take Pletal if you have a known allergy to cilostazol or any ingredients in the medicine. An allergic reaction can be serious and requires immediate medical attention.
Do not take if you have active bleeding or a known bleeding disorder. Cilostazol’s effects on platelets can increase bleeding risk in certain contexts.
Do not take if you have severe heart failure or certain heart rhythm problems without a clinician’s evaluation. This requires careful assessment of benefits and risks for your heart health.
Do not take if you have severe liver disease or significant kidney disease. Severe organ impairment may affect how the medicine works and safety.
Pregnant or planning pregnancy and breastfeeding individuals should discuss alternatives with a clinician. The safety of cilostazol in pregnancy and lactation is not established for all situations.
Common warnings include dizziness, headaches, flushing, and stomach upset. If these become troublesome, discuss management options with your clinician.
Pletal can cause changes in heart rate and blood pressure. Some people feel palpitations or lightheadedness, especially when standing up quickly. If you notice fainting or very severe dizziness, seek medical advice promptly.
Because cilostazol affects platelets, there is a potential for increased bleeding or bruising, particularly when used with other blood-thinning medicines or when you have a wound or surgery planned. Always inform your clinician about all medicines you take, including over-the-counter drugs, vitamins, and herbal supplements.
Kidney or liver function: if you have significant liver or kidney disease, your clinician may monitor you more closely or adjust treatment. Report signs of liver trouble (jaundice, dark urine, pale stools) or unusual swelling in the legs or abdomen.
Regular medical review is important. Your clinician may periodically reassess the need for continuing therapy and check for side effects or interactions with other medicines. If you notice new symptoms or if existing symptoms worsen, contact your healthcare provider.
Common side effects include headache, dizziness, upset stomach, diarrhea, and flushing. These are usually mild and may improve with time or with a dose adjustment under supervision.
Less common effects may include palpitations, swelling of the ankles or legs, or skin rash. If these occur or persist, discuss them with your clinician.
There are rare but serious side effects that require urgent medical attention. Seek help immediately if you experience severe chest pain, signs of a heart attack, heavy or unexplained bleeding, severe allergic reactions (swelling of the face or throat, trouble breathing), or fainting with exertion.
Other potential but uncommon effects can include changes in vision, persistent abdominal pain, or severe muscle cramps. Report anything unusual to your healthcare provider so it can be evaluated properly.
Cilostazol levels in the body can be changed by other medicines that affect liver enzymes. Always tell your clinician about every medicine you take, including over‑the‑counter drugs and herbal products.
Taking cilostazol with other anticoagulants or antiplatelet drugs (for example, aspirin or warfarin) can raise the risk of bleeding. Your clinician will weigh the benefits and risks if these medicines are used together.
Some antifungal, antibiotic, antiviral, or cholesterol-lowering medicines can affect how cilostazol is metabolized. Your clinician may adjust the dose or monitor you more closely if such drugs are necessary for your treatment.
Grapefruit products or large amounts of grapefruit juice may influence the way cilostazol is processed by the body. If you consume grapefruit regularly, discuss this with your clinician. Always follow product labeling and professional guidance about food interactions.
If you notice unusual bleeding, severe bruising, or significant dizziness after starting or changing medicines, contact your clinician promptly.
There is limited data on cilostazol use in pregnancy. It should be used during pregnancy only if clearly needed and after careful consideration with a clinician.
Pregnant individuals should discuss potential alternatives and risks with their healthcare provider before starting this medicine.
It is not known whether cilostazol passes into human breast milk. If you are breastfeeding or planning to breastfeed, talk with your clinician about whether this medicine is appropriate for you and your baby.
As with all medications, the potential benefits and risks should be weighed with a clinician when pregnancy or lactation is a consideration.
Most people notice improvement after several weeks of regular use, but response varies. Some people may perceive benefits earlier, while others may need a longer period to assess effectiveness. If there is no improvement after a reasonable trial period, discuss this with your clinician.
If you remember soon after missing a dose, take it as soon as you can. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double up to catch up.
Moderation is advised. Alcohol can affect blood pressure and cause dizziness in some people. Discuss your drinking habits with your clinician to ensure safety while on therapy.
Treatment duration is decided by your clinician based on symptoms, response, and tolerance. Long-term therapy is possible for some patients, with regular follow‑up to monitor safety and effectiveness.
Yes, but some combinations can increase bleeding risk or cause other interactions. Always inform your clinician about all medicines you take, including over‑the‑counter products and supplements, before starting or stopping any drug.
Seek urgent medical help if you experience chest pain, fainting, severe dizziness, or other severe symptoms. Do not ignore warning signs that could indicate a serious problem.
It can influence certain laboratory tests in some people. If you have blood tests, tell your healthcare team that you are taking cilostazol so they interpret results correctly.
Pregnancy requires careful consideration of risks and benefits. If you become pregnant while taking this medicine, contact your clinician promptly to discuss options.
A sudden stop can sometimes worsen symptoms or cause other issues. Do not stop the medication abruptly without consulting your clinician, who can advise a safe plan for tapering if needed.
The requirement for a prescription can vary with local rules. In New Zealand, a clinician will determine whether a prescription is required for you, and a pharmacist can provide guidance based on the official NZ leaflet and regulatory guidance.
Dizziness or lightheadedness can occur in some people and may affect your ability to drive. If you feel unsteady, postpone driving or contact your clinician for advice.
Always read the official patient information leaflet that accompanies the medicine for detailed instructions, warnings, and storage information. The leaflet is prepared by the manufacturer and approved by health regulators.
Ask your pharmacist for the Medicines Information Sheet or a plain-language summary that explains how cilostazol works, possible side effects, and what to watch for during treatment.
In New Zealand, your GP, specialist, or pharmacist can answer questions about Pletal and how it fits with your overall plan. If you need formal guidance, discuss the NZ regulatory documents and the official leaflets with a healthcare professional.
If you have concerns about drug interactions, allergies, or how Pletal may affect other conditions you have, contact your clinician promptly. For acute advice or urgent concerns, seek medical attention through the appropriate local services. This information is not a substitute for professional medical advice.
14–21 days. Free from NZ$342.37 .
5–9 days. NZ$51.36
−10% when paying with cryptocurrency.
−10% on all repeat orders.
All orders are packed in neutral, unbranded boxes with no product name on the outside.
