Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 250mg | ||||
360 pill | 250mg | NZD495.99 | NZD1.38 | |
180 pill | 250mg | NZD266.67 | NZD1.48 | |
120 pill | 250mg | NZD193.63 | NZD1.61 | |
90 pill | 250mg | NZD156.26 | NZD1.73 | |
60 pill | 250mg | NZD113.79 | NZD1.89 | |
30 pill | 250mg | NZD64.53 | NZD2.14 | |
Dosage: 500mg | ||||
90 pill | 500mg | NZD169.85 | NZD1.89 | |
60 pill | 500mg | NZD118.89 | NZD1.99 | |
30 pill | 500mg | NZD64.53 | NZD2.12 |

Chloramphenicol Description
Introduction to Chloramphenicol
Chloramphenicol is a potent antibiotic that has been used for decades to treat a variety of bacterial infections. It was first discovered in the late 1940s and quickly became a vital addition to the medical arsenal due to its broad-spectrum activity. Despite its efficacy, it is often reserved for specific cases because of potential side effects and the availability of newer antibiotics. When used appropriately, chloramphenicol can effectively combat serious infections caused by susceptible bacteria.
How Chloramphenicol Works
This medication functions by inhibiting protein synthesis in bacteria. It binds to the 50S subunit of the bacterial ribosome, preventing the formation of peptide bonds. This action interrupts bacterial growth and multiplication, giving the immune system a better chance to eliminate the infection. Its broad-spectrum activity means it can target various gram-positive and gram-negative bacteria, making it useful for treating diverse infections.
Uses and Applications
Chloramphenicol is commonly prescribed for infections like typhoid fever, bacterial conjunctivitis, meningitis, and certain ocular infections. Due to its effectiveness, it is sometimes used in cases where other antibiotics are ineffective or contraindicated. However, because of the potential for serious side effects, its use is often limited to specific situations under careful medical supervision. In some regions, it is still used in topical forms for eye and ear infections, providing localized treatment with fewer systemic risks.
Potential Side Effects
While chloramphenicol can be highly effective, it carries a risk of severe adverse reactions. The most concerning is aplastic anemia, a rare but potentially fatal condition that affects the bone marrow’s ability to produce blood cells. This side effect is unpredictable and can occur even after short courses of treatment. Other possible side effects include allergic reactions, gastrointestinal disturbances, and grey baby syndrome in newborns. Because of these risks, healthcare providers carefully weigh the benefits and dangers before prescribing this medication.
Precautions and Warnings
Chloramphenicol should be used with caution, especially in vulnerable populations like pregnant women, nursing mothers, and infants. Monitoring blood counts during treatment is often recommended to detect early signs of hematological toxicity. Patients with liver or kidney impairment may require dosage adjustments. It's crucial to follow medical guidance strictly when using this medication to minimize risks and ensure effective treatment outcomes.
Availability and Usage Guidelines
Chloramphenicol is available in various forms, including capsules, injectable solutions, and topical preparations. The dosage and duration depend on the type and severity of the infection, as well as patient-specific factors. Always adhere to healthcare provider instructions and complete the full course of therapy to avoid resistance and relapse. Self-medication or improper use can increase the likelihood of side effects and diminish the drug’s effectiveness.
Conclusion
Chloramphenicol remains a valuable antibiotic under specific circumstances. Its broad activity makes it an option for serious infections resistant to other treatments. However, due to its potential serious side effects, its use requires careful medical supervision. Proper patient selection, dosing, and monitoring are essential to maximize benefits while minimizing risks. When used responsibly, chloramphenicol can be an effective tool in combating bacterial infections that threaten health and wellbeing.
See Also
